Argentina looks to continue their dominance of the South American qualifying group when they face Chile, who is teetering on the brink of failing to qualify for the 2014 World Cup.
Former Argentine player and current coach Alejandro Sabella will look to dominate the match offensively, with three of the world top strikers slated to be starting.
Lionel Messi, arguably the world's best forward, has been dominant so far this year, and looks to continue his goal-scoring prowess when they travel to Santiago's Julio Martinez Pradanos national stadium. Messi recorded two more goals during his team's 3-0 win over Uruguay.
Gonzalo Higuain, who typically plays opposite Messi during league play in Spain, will surely welcome the beautiful play that he brings to the field along with Sergio Aguero.
Aguero's tenacity in particular helped secure full points during their last match. It was that same tenacity that led Manchester City over Queens Park Rangers in the final match of the Premier League season, securing the championship for his side.
Chile sits fifth in the group and after two poor performances against Columbia and Ecuador, coach Claudio Borghi is certainly feeling pressure, given the rising tide of calls to have him fired.
To offset his team's poor offensive showing- they netted only two goals in the past two matches while conceding six- Borhgi will look to have a more offensive minded approach to this match as a way to overcome the current group leaders. However, he will have to overcome the absence of some veteran players.
Osvaldo Gonzalez, Michael Contreras and Arturo Vidal will all not play, along with goalkeeper Miguel Pinto, who is injured. But the team should welcome the return of Gary Medel in midfield.
Three players that are slated to start have yet to earn a cap, but all of whom have come through the Chilean youth system. Angelo Henriquez, defender Igor Lichnovsky and midfielder Sebastian Martinez will look to lend their youthful exuberance against a dominant Argentinian side.
Kickoff for the match is at 8:05 EDT and can be watched online here.