Chelsea travel crosstown to visit Tottenham at White Hart Lane on Saturday in what is an early test for two top clubs in addition to being a competitively fierce London derby.
Spurs boss Andre Villa-Boas has led his side to an impressive start to the season after acquiring some key players in the wake of Welsh international Gareth Bale's departure to Real Madrid.
Spurs have earned 12 points from five games and are level with arch-rivals Arsenal at the top of the Premier League standings.
Enabling such an early season surge Tottenham have the top defense in the division conceding just once this season. Chelsea has also been buoyed by their defense conceding just one more than Spurs.
Both managers will be looking for production from their respective signings as both clubs look to overcome injuries to regular starters.
Left-back Danny Rose is likely to make his return from a toe injury for Tottenham, but defender Younes Kaboul and midfielder Étienne Capoue remain doubtful.
Spurs will give winger Aaron Lennon a fitness test while striker Emmanuel Adebayor is out through illness.
For Chelsea, they will make a game time decision to see if midfielder Ramires is fit to face Spurs.
The Brazilian suffered a hip injury in Tuesday night's Capital One Cup win at Swindon and was taken off at half-time, but Jose Mourinho hopes to include him in a much-changed line-up at White Hart Lane.
Ramires had replaced Marco van Ginkel, who is out for six months, after undergoing knee surgery to repair a torn anterior cruciate ligament.
Kick-off for the match is at 7:45 a.m. ET and can be watched online here.