Khloe Kardashian, Lamar Odom Divorce Rumors: NBA Star Missing for 72 Hours Amid Addiction Rumors?

Khloe Kardashian-Odom is reacting to speculation about her husband NBA player Lamar Odom's infidelity along with allegations of his drug use.

Odom, 33, has made headlines in recent weeks for allegedly stepping out on his marriage and now recent TMZ reports have stated that his wife asked him to leave because of a drug addiction that he refused to get help for.

Although TMZ reports allege that Odom has been battling an addiction to crack cocaine for two years, the publication also stated that he was missing for 72 hours over the weekend. Kardashian-Odom, 29, took to Twitter amid the media reports concerning her marriage and her husband's alleged issues with addiction.

"Really hard to sit here and listen to people talk (expletive) about my family," Kardashian-Odom tweeted. "(Expletive) you and shame on you! I'm too protective for this (expletive)!"

Odom has previously revealed that he had a harsh upbringing including facing the death of his mother when he was just 12, and father who was a heroin addict.

"My father's a heroin addict," Odom said during an episode of the reality television show with his wife, "Khloe & Lamar." "I had my mother around until I was 12 years old when she passed away and after that my father wasn't around..I witnessed things that a 10-year-old definitely wasn't supposed to see.."

Although Odom has been the subject of media speculation, a number of people on Twitter felt compelled to pray for the NBA free agent.

"Y'all pray for Lamar Odom," one person tweeted. "That man is going through some things."

Another individual spoke about others that need to stop being so critical of Odom.

"Let's not be so critical of @RealLamarOdom but let's All Come Together & Pray 4 Him so he will come through this .. I LOVE U L.O.,(SIC)" another person tweeted.