League Cup champions Swansea City host Arsenal at the Liberty Stadium on Saturday in the afternoon late kick off, after both teams were in action midweek.
Cup holders Swansea were knocked out of the tournament after losing 3-1 to Birmingham, while Arsenal was able to overcome West Brom at The Hawthorns after a penalty shootout.
After losing 3-1 at home on opening day to Aston Villa, Arsene Wenger has rallied his team in the group stages of the Champions League and to the top of the English Premier League table.
Arsenal have won four league games in a row and can equal their best run of Premier League away wins if they win on Saturday.
But Michael Laudrup's side are playing well having won two of their last three league games while also beating Spanish side Valencia 3-0 at the Mestalla in the Europa League.
Arsenal won this fixture 2-0 last season, but Swansea gained revenge by securing a 2-0 win of their own in the return game to level the head to head record in league encounters at four wins each from eight matches.
Injury news may pose a problem for Swansea since captain Ashley Williams is doubtful. The Wales defender has been struggling with an ankle injury and manager Michael Laudrup says he has less than a 50 percent chance of featuring against the Gunners. Pablo Hernández will again miss out due to a hamstring injury.
Arsenal will also be watching injury reports closely and will give fitness tests to midfielder Aaron Ramsey and Mathieu Flamini ahead of Saturday's match.
England forward Theo Walcott has responded well to surgery on a minor abdominal problem, but is now set for up to five weeks recovery.
Czech playmaker Tomas Rosicky could return for next week's Champions League game against Napoli, but Santi Cazorla, Yaya Sanogo, Lukas Podolski, Alex Oxlade-Chamberlain and Abou Diaby are all out.
Kick-off for the match is at 12:30 p.m. ET and can be watched online here.